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The flavanone pinostrobin in the synthesis of coumarin-chalcone hybrids with a triazole linker Full article

Journal Chemistry of Heterocyclic Compounds
ISSN: 0009-3122 , E-ISSN: 1573-8353
Output data Year: 2015, Volume: 51, Number: 2, Pages: 146-152 Pages count : DOI: 10.1007/s10593-015-1672-y
Tags 7-alkynylcoumarins; azide; 2-(bromoalkoxy)chalcones; pinostrobin; 1,2,3-triazoles
Authors Mukusheva Gulim K. 1 , Lipeeva Alla V. 2 , Zhanymkhanova Pernesh Zh. 1 , Shults Elvira E. 2,3 , Gatilov Yurii V. 2,3 , Shakirov Makhmut M. 2 , Adekenov Sergazy M. 1
Affiliations
1 (Данные Web of science) Int Res & Prod Holding Phytochem, Karaganda 100009, Kazakhstan
2 (Данные Web of science) Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia
3 (Данные Web of science) Novosibirsk State Natl Res Univ, Novosibirsk 630090, Russia

Abstract: The reaction of flavanone pinostrobin with dibromoalkanes in acetone in the presence of potassium carbonate followed the path of retro-Michael addition - D-alkylation and resulted in the formation of the respective 2-(bromoalkoxy)chalcones. Treatment of the latter with sodium azide gave the respective azides, which were highly active in the Du-catalyzed 1,3-dipolar cycloaddition reaction. The reaction of these azides with 6-substituted 7-ethynylcoumarins gave coumarin-chalcone hybrids containing a 1,2,3-triazole linker.
Cite: Mukusheva G.K. , Lipeeva A.V. , Zhanymkhanova P.Z. , Shults E.E. , Gatilov Y.V. , Shakirov M.M. , Adekenov S.M.
The flavanone pinostrobin in the synthesis of coumarin-chalcone hybrids with a triazole linker
Chemistry of Heterocyclic Compounds. 2015. V.51. N2. P.146-152. DOI: 10.1007/s10593-015-1672-y WOS Scopus РИНЦ OpenAlex
Dates:
Published print: Feb 1, 2015
Published online: Apr 3, 2015
Identifiers:
Web of science: WOS:000353057900005
Scopus: 2-s2.0-84953352637
Elibrary: 27568503
OpenAlex: W2071155188
Citing:
DB Citing
Web of science 13
Scopus 15
Elibrary 15
OpenAlex 12
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