The flavanone pinostrobin in the synthesis of coumarin-chalcone hybrids with a triazole linker Full article
Journal |
Chemistry of Heterocyclic Compounds
ISSN: 0009-3122 , E-ISSN: 1573-8353 |
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Output data | Year: 2015, Volume: 51, Number: 2, Pages: 146-152 Pages count : DOI: 10.1007/s10593-015-1672-y | ||||||
Tags | 7-alkynylcoumarins; azide; 2-(bromoalkoxy)chalcones; pinostrobin; 1,2,3-triazoles | ||||||
Authors |
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Abstract:
The reaction of flavanone pinostrobin with dibromoalkanes in acetone in the presence of potassium carbonate followed the path of retro-Michael addition - D-alkylation and resulted in the formation of the respective 2-(bromoalkoxy)chalcones. Treatment of the latter with sodium azide gave the respective azides, which were highly active in the Du-catalyzed 1,3-dipolar cycloaddition reaction. The reaction of these azides with 6-substituted 7-ethynylcoumarins gave coumarin-chalcone hybrids containing a 1,2,3-triazole linker.
Cite:
Mukusheva G.K.
, Lipeeva A.V.
, Zhanymkhanova P.Z.
, Shults E.E.
, Gatilov Y.V.
, Shakirov M.M.
, Adekenov S.M.
The flavanone pinostrobin in the synthesis of coumarin-chalcone hybrids with a triazole linker
Chemistry of Heterocyclic Compounds. 2015. V.51. N2. P.146-152. DOI: 10.1007/s10593-015-1672-y WOS Scopus РИНЦ OpenAlex
The flavanone pinostrobin in the synthesis of coumarin-chalcone hybrids with a triazole linker
Chemistry of Heterocyclic Compounds. 2015. V.51. N2. P.146-152. DOI: 10.1007/s10593-015-1672-y WOS Scopus РИНЦ OpenAlex
Dates:
Published print: | Feb 1, 2015 |
Published online: | Apr 3, 2015 |
Identifiers:
Web of science: | WOS:000353057900005 |
Scopus: | 2-s2.0-84953352637 |
Elibrary: | 27568503 |
OpenAlex: | W2071155188 |