Development and Application of Spin Traps, Spin Probes, and Spin Labels

Development and Application of Spin Traps, Spin Probes, and Spin Labels Full article

Journal

Methods in Enzymology
ISSN: 0076-6879

Output data

Year: 2015, Volume: 563, Pages: 365-396 Pages count : DOI: 10.1016/bs.mie.2015.06.004

Tags

DNA; DQC; EPR; Nitrones; Nitroxide; Organic synthesis; PELDOR/DEER; Spin labels; Spin traps; Trityl radicals

Authors

Bagryanskaya Elena G. ^1,2 , Krumkacheva Olesya A. ^2,3 , Fedin Matvey V. ^2,3 , Marque Sylvain R. A. ⁴

Affiliations

1	(Данные Web of science) NN Vorozhtsov Novosibirsk Inst Organ Chem SB RAS, Novosibirsk, Russia
2	(Данные Web of science) Novosibirsk State Univ, Novosibirsk 630090, Russia
3	(Данные Web of science) Int Tomog Ctr SB RAS, Novosibirsk, Russia
4	(Данные Web of science) Aix Marseille Univ, Marseille, France

This chapter focuses on major achievements of the last decade in the synthesis and applications of spin traps, spin probes, and spin labels. Our discussion on spin trapping is mainly concerned with novel aspects of nitrones used as spin traps and with the kinetics caused by bioreductants. The second part of the chapter deals with recent developments in site-directed spin labeling (SDSL) for studying structure and functions of proteins and nucleic acids. We focus on SDSL EPR distance measurements using advanced trityl and nitroxide labels, on new approaches for incorporation of spin labels in biomolecules, and finally, on recent room/physiological temperature measurements made feasible by these novel spin labels.

Bagryanskaya E.G. , Krumkacheva O.A. , Fedin M.V. , Marque S.R.A.
Development and Application of Spin Traps, Spin Probes, and Spin Labels
Methods in Enzymology. 2015. V.563. P.365-396. DOI: 10.1016/bs.mie.2015.06.004 WOS Scopus РИНЦ OpenAlex

Web of science:	WOS:000376156800015
Scopus:	2-s2.0-84944355293
Elibrary:	24961607
OpenAlex:	W2415243421

DB	Citing
Web of science	49
Scopus	46
Elibrary	47
OpenAlex	47