Direct di- and triamination of polyfluoropyridines in anhydrous ammonia

Direct di- and triamination of polyfluoropyridines in anhydrous ammonia Научная публикация

Журнал

Journal of Fluorine Chemistry
ISSN: 0022-1139

Вых. Данные

Год: 2009, Том: 130, Номер: 5, Страницы: 461-465 Страниц : DOI: 10.1016/j.jfluchem.2009.02.005

Ключевые слова

Polyfluoropyridines; Diaminopyridines; Triaminopyridines; Anhydrous ammonia; Aminodefluorination; Nucleophilic substitution

Авторы

Kusov Soltan Z. ¹ , Rodionov Vladimir I. ¹ , Vaganova Tamara A. ¹ , Shundrina Inna K. ¹ , Malykhin Evgenij V. ¹

Организации

1	(Данные Web of science) Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia

Aminodefluorination of polyfluoropyridines (pentafluoro-, 3,5-dichlorotrifluoro-, 3- and 4-chlorotetrafluoro, 2,3,5,6- and 2,3,4,6-tetrafluoro-, 3-chloro-2,4,6-trifluoro-, and 2,4,6-trifluoropyridine) in anhydrous ammonia has been investigated. Temperatures of the second and third amino group introduction into pyridine ring were shown to increase significantly thus ensuring conditions for selective preparation of mono-, di- and, in the case of perhalopyridines as starting compounds, triaminoderivatives with high yield and purity. (C) 2009 Elsevier B.V. All rights reserved.

Kusov S.Z. , Rodionov V.I. , Vaganova T.A. , Shundrina I.K. , Malykhin E.V.
Direct di- and triamination of polyfluoropyridines in anhydrous ammonia
Journal of Fluorine Chemistry. 2009. V.130. N5. P.461-465. DOI: 10.1016/j.jfluchem.2009.02.005 WOS Scopus РИНЦ

Опубликована в печати:

1 мая 2009 г.

Web of science	WOS:000266953500002
Scopus	2-s2.0-67349086221
РИНЦ	13601587
OpenAlex	W2149030792