Data for isolation and properties analysis of diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotide

Data for isolation and properties analysis of diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotide Научная публикация

Журнал

Data in Brief
ISSN: 2352-3409

Вых. Данные

Год: 2019, Том: 25, Номер статьи : 104148, Страниц : DOI: 10.1016/j.dib.2019.104148

Ключевые слова

Phosphoryl guanidine oligonucleotide; RP-HPLC; Circular dichroism; NMR; Molecular dynamics; Diastereomer assignment phosphodiesterase digestion assay; Spatial structure

Авторы

Lomzov Alexander A. ^1,3 , Kupryushkin Maxim S. ¹ , Shernyukov Andrey V. ^2,3 , Nekrasov Mikhail D. ¹ , Dovydenko Ilya S. ¹ , Stetsenko Dmitry A. ^1,3 , Pyshnyi Dmitrii V. ^1,3

Организации

1	(Данные Web of science) RAS, SB, Inst Chem Biol & Fundamental Med, 8 Lavrentiev Ave, Novosibirsk 630090, Russia
2	(Данные Web of science) RAS, SB, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Lavrentiev Ave, Novosibirsk 630090, Russia
3	(Данные Web of science) Novosibirsk State Univ, 2 Pirogova St, Novosibirsk 630090, Russia

This article presents new data on the properties of the diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotides d(TpCp*A) [1,2]. The data include information on isolation, identification, treatment with snake venom phosphodiesterase and structural analysis by 1D and 2D NMR spectroscopy and restrained molecular dynamics analysis. The data can be used for preparation, analysis, application of phosphoryl guanidine oligonucleotide and for development of new nucleic acids derivatives. This data article is associated with the manuscript titled "Diastereomers of a mono- substituted phosphoryl guanidine trideoxyribonucleotide: isolation and properties" [1]. (c) 2019 The Authors. Published by Elsevier Inc.

Lomzov A.A. , Kupryushkin M.S. , Shernyukov A.V. , Nekrasov M.D. , Dovydenko I.S. , Stetsenko D.A. , Pyshnyi D.V.
Data for isolation and properties analysis of diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotide

Data in Brief. 2019. V.25. 104148 . DOI: 10.1016/j.dib.2019.104148 WOS Scopus РИНЦ

Полный текст от издателя

Опубликована в печати:

1 авг. 2019 г.

Web of science	WOS:000495104500174
Scopus	2-s2.0-85068078720
РИНЦ	41648148
OpenAlex	W2953111172