STUDYING DEPENDENCES BETWEEN THE CHEMOTYPE STRUCTURE OF SOME NATURAL COMPOUNDS AND THE SPECTRUM OF THEIR TARGETED ACTIVITIES CORRELATED WITH THE HYPOGLYCEMIC EFFECT

STUDYING DEPENDENCES BETWEEN THE CHEMOTYPE STRUCTURE OF SOME NATURAL COMPOUNDS AND THE SPECTRUM OF THEIR TARGETED ACTIVITIES CORRELATED WITH THE HYPOGLYCEMIC EFFECT Научная публикация

Журнал

Journal of Structural Chemistry
ISSN: 0022-4766 , E-ISSN: 1573-8779

Вых. Данные

Год: 2019, Том: 60, Номер: 11, Страницы: 1827-1832 Страниц : 6 DOI: 10.1134/S0022476619110179

Ключевые слова

natural compounds; terpenoids; polyphenols; hypoglycemic activity; in silico; QSAR; Microcosm BioS; multitargeted action; prediction of the targeted activity spectrum

Авторы

Vasilyev P.M. ¹ , Luzina O.A. ² , Babkov D.A. ¹ , Appazova D.T. ¹ , Salakhutdinov N.F. ^2,3 , Spasov A.A. ¹

Организации

1	(Данные Web of science) Volgograd State Med Univ, Volgograd, Russia
2	(Данные Web of science) Russian Acad Sci, Vorozhtsov Inst Organ Chem, Siberian Branch, Novosibirsk, Russia
3	(Данные Web of science) Novosibirsk State Univ, Novosibirsk, Russia

The method of similarity to standards is used to calculate the spectrum of targeted hypoglycemic activities of a series of natural compounds of terpenoid and polyphenol classes. Some compounds are shown to be promising multitargeted hypoglycemic agents. Primary action targets are identified.

Vasilyev P.M. , Luzina O.A. , Babkov D.A. , Appazova D.T. , Salakhutdinov N.F. , Spasov A.A.
STUDYING DEPENDENCES BETWEEN THE CHEMOTYPE STRUCTURE OF SOME NATURAL COMPOUNDS AND THE SPECTRUM OF THEIR TARGETED ACTIVITIES CORRELATED WITH THE HYPOGLYCEMIC EFFECT
Journal of Structural Chemistry. 2019. V.60. N11. P.1827-1832. DOI: 10.1134/S0022476619110179 WOS Scopus РИНЦ

Васильев П.M. , Лузина О.А. , Бабков Д.А. , Аппазова Д.Т. , Салахутдинов Н.Ф. , Спасов А.А.
Исследование зависимости между структурой хемотипов некоторых природных соединений и спектром их таргетных активностей, соотносимых с гипогликемическим действием
Журнал структурной химии (J STRUCT CHEM+). 2019. Т.60. №11. С.1901-1906. DOI: 10.26902/JSC_id48260 РИНЦ

Опубликована в печати:	1 нояб. 2019 г.
Опубликована online:	17 дек. 2019 г.

Web of science	WOS:000511607700017
Scopus	2-s2.0-85076548935
РИНЦ	43218474
OpenAlex	W2996255090