Antiarrhythmic activity of 4,6-di(het)aryl-5-nitro-3,4-dihydropyrimidin-(1 H)-2-ones and its effects on arterial pressure in rats

Antiarrhythmic activity of 4,6-di(het)aryl-5-nitro-3,4-dihydropyrimidin-(1 H)-2-ones and its effects on arterial pressure in rats Научная публикация

Журнал

Bioorganic and Medicinal Chemistry Letters
ISSN: 0960-894X , E-ISSN: 1464-3405

Вых. Данные

Год: 2006, Том: 16, Номер: 5, Страницы: 1418-1420 Страниц : 3 DOI: 10.1016/j.bmcl.2005.11.043

Ключевые слова

antiarrhythmic activity; 4,6-di(het)aryl-5-nitro-3,4-dihydropyrimidin-(1H)-2-ones; arrhythmia

Авторы

Bryzgalov AO ¹ , Dolgikh MP ¹ , Sorokina IV ¹ , Tolstikova TG ¹ , Sedova VF ¹ , Shkurko OP ¹

Организации

1	(Данные Web of science) Russian Acad Sci, NN Vorozhtsov Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia

The antiarrhythmic activity of 4,6-di(het)aryl-5-nitro-3,4-dihydropyrimidin-(1H)-2-ones toward two types of experimental rat arrhythmia has been studied. With CaCl2 induced arrhythmia model, several agents have demonstrated high antiarrhythmic activity and the lack of influence on arterial pressure of rats. (C) 2005 Elsevier Ltd. All rights reserved.

Bryzgalov A. , Dolgikh M. , Sorokina I. , Tolstikova T. , Sedova V. , Shkurko O.
Antiarrhythmic activity of 4,6-di(het)aryl-5-nitro-3,4-dihydropyrimidin-(1 H)-2-ones and its effects on arterial pressure in rats
Bioorganic and Medicinal Chemistry Letters. 2006. V.16. N5. P.1418-1420. DOI: 10.1016/j.bmcl.2005.11.043 WOS Scopus РИНЦ

Опубликована в печати:

1 мар. 2006 г.

Web of science	WOS:000235284700068
Scopus	2-s2.0-31344473762
РИНЦ	13509363
OpenAlex	W2029708001