Dihydropyrimidin-2(1H)-one and its analogues as a platform for the design and synthesis of new biologically active compounds

Dihydropyrimidin-2(1H)-one and its analogues as a platform for the design and synthesis of new biologically active compounds Научная публикация

Журнал

Russian Chemical Reviews
ISSN: 0036-021X , E-ISSN: 1468-4837

Вых. Данные

Год: 2016, Том: 85, Номер: 10, Страницы: 1056-1096 Страниц : 41 DOI: 10.1070/RCR4586

Авторы

Shkurko Oleg P. ¹ , Tolstikova Tatiana G. ¹ , Sedova Valentina F. ¹

Организации

1	(Данные Web of science) Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, Prosp Akad Lavrentieva 9, Novosibirsk 630090, Russia

The data published mainly over two past decades on various types of biological activity of 5-functionally substituted 3,4-dihydropyrimidin-2-ones and their analogues, 2-thiones and 2-imines, and more complex dihydropyrimidine derivatives are summarized. Apart from medicinal chemistry issues, including structure activity relationships, the pharmacological profiles of the most promising derivatives and the routes for further structural modification of known chemical compounds are discussed in general terms. Examples of potential uses of new compounds in medicine as single pharmaceutical agents and as parts of compositions are given.

Shkurko O.P. , Tolstikova T.G. , Sedova V.F.
Dihydropyrimidin-2(1H)-one and its analogues as a platform for the design and synthesis of new biologically active compounds
Russian Chemical Reviews. 2016. V.85. N10. P.1056-1096. DOI: 10.1070/RCR4586 WOS Scopus РИНЦ

Шкурко О.П. , Толстикова Т.Г. , Седова В.Ф.
Дигидропиримидин-2(1h)-он и его аналоги как платформа для конструирования и синтеза новых биологически активных соединений
Успехи химии/Uspekhi Khimii. 2016. Т.85. №10. С.1056-1096. РИНЦ

Опубликована в печати:	31 окт. 2016 г.
Опубликована online:	31 окт. 2016 г.

Web of science	WOS:000391302300002
Scopus	2-s2.0-84994116092
РИНЦ	32803212
OpenAlex	W2471195113