Reaction of polyfluorinated chalcones with guanidine

Reaction of polyfluorinated chalcones with guanidine Научная публикация

Журнал

Russian Journal of Organic Chemistry
ISSN: 1070-4280 , E-ISSN: 1608-3393

Вых. Данные

Год: 2015, Том: 51, Номер: 12, Страницы: 1745-1752 Страниц : 8 DOI: 10.1134/S1070428015120143

Авторы

Borodina E.A. ¹ , Orlova N.A. ¹ , Gatilov Yu V. ^1,2 , Sal'nikova O.I. ¹

Организации

1	(Данные Web of science) Russian Acad Sci, Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Pr Akad Lavrenteva 9, Novosibirsk 630090, Russia
2	(Данные Web of science) Novosibirsk State Univ, Novosibirsk 630090, Russia

Reactions of polyfluorinated chalcones with guanidine in the presence of bases are accompanied by elimination of the polyfluorophenyl group. 3-(Pentafluorophenyl)-1-phenylprop-2-en-1-one and its derivatives reacted with guanidine under basic conditions to give 4-phenylpyrimidin-2-amine, polyfluorobenzenes, and Michael adducts, 3-(2-amino-4-phenylpyrimidin-5-yl)-3-(4-R-2,3,5,6-tetrafluorophenyl)-1-phenylpropan-1-ones. 1-(Pentafluorophenyl)-3-phenylprop-2-en-1-one and 1,3-bis(pentafluorophenyl)prop-2-en-1-one were converted into cinnamic acid derivatives whose reaction with guanidine afforded 2-amino-6-aryl-5,6-dihydropyrimidin-4(1H)-ones.

Borodina E.A. , Orlova N.A. , Gatilov Y.V. , Sal'nikova O.I.
Reaction of polyfluorinated chalcones with guanidine
Russian Journal of Organic Chemistry. 2015. V.51. N12. P.1745-1752. DOI: 10.1134/S1070428015120143 WOS Scopus РИНЦ

Соболева Е.А. , Орлова Н.А. , Гатилов Ю.В. , Сальникова О.И.
Взаимодействие полифторхалконов с гуанидином
Журнал органической химии (RUSS J ORG CHEM+). 2015. Т.51. №12. С.1778-1785. РИНЦ

Опубликована в печати:	1 дек. 2015 г.
Опубликована online:	23 янв. 2016 г.

Web of science	WOS:000368737400014
Scopus	2-s2.0-84955440241
РИНЦ	26843243
OpenAlex	W2340405474