Synthesis of Derivatives of the Optically Active beta-Amino Acids from (+)-Car-2-ene

Synthesis of Derivatives of the Optically Active beta-Amino Acids from (+)-Car-2-ene Full article

Journal

Helvetica Chimica Acta
ISSN: 0018-019X , E-ISSN: 1522-2675

Output data

Year: 2008, Volume: 91, Number: 10, Pages: 1849-1856 Pages count : DOI: 10.1002/hlca.200890197

Authors

Koneva Ekaterina A. , Volcho Konstantin P. , Gatilov Yuri V. , Korchagina Dina V. , Salnikov Georgi E. , Salakhutdinov Nariman F.

Affiliations

1	(Данные Web of science) Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia

The reaction of (+)-car-2-ene (4) with chlorosulfonyl isocyanate (=sulfuryl chloride isocyanate; CISO2NCO) led to the tricyclic lactams 6 and 8 corresponding to the initial formation both of the tertiary carbenium and alpha-cyclopropylcarbenium ions (Scheme 2). A number of optically active derivatives of beta-amino acids which are promising compounds for further use in asymmetric synthesis were synthesized from the lactams (see 16, 17, and 19-21 in Scheme 3).

Koneva E.A. , Volcho K.P. , Gatilov Y.V. , Korchagina D.V. , Salnikov G.E. , Salakhutdinov N.F.
Synthesis of Derivatives of the Optically Active beta-Amino Acids from (+)-Car-2-ene
Helvetica Chimica Acta. 2008. V.91. N10. P.1849-1856. DOI: 10.1002/hlca.200890197 WOS Scopus РИНЦ

Published print:

Oct 1, 2008

Web of science	WOS:000261050300004
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