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Use of the Mannich Reaction to Synthesize Spin-Labeled Derivatives of the Natural Flavonoid Dihydroquercetin Научная публикация

Журнал Chemistry of Natural Compounds
ISSN: 0009-3130 , E-ISSN: 1573-8388
Вых. Данные Год: 2014, Том: 50, Номер: 2, Страницы: 261-265 Страниц : DOI: 10.1007/s10600-014-0927-7
Ключевые слова dihydroquercetin; nitroxyl radicals; spin-labeled compounds; Mannich reaction
Авторы Kosheleva N. V. 1 , Chernyak E. I. 1 , Polienko Yu F. 1 , Morozov S. V. 1 , Grigor'ev I. A. 1
Организации
1 (Данные Web of science) Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia

Реферат: Mono-substituted spin-labeled compounds were synthesized from Mannich reactions of dihydroquercetin with 4-amino-2,2,6,6-tetramethylpiperidine-1-oxyl, 3-amino-2,2,5,5-tetramethylpyrrolidine-1-oxyl, and 3-aminomethyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl. According to preliminary data, the compounds possessed antioxidant activity and selective cytotoxicity against various tumor cells and were promising for biomedical tests including magnetic resonance tomography.
Библиографическая ссылка: Kosheleva N.V. , Chernyak E.I. , Polienko Y.F. , Morozov S.V. , Grigor'ev I.A.
Use of the Mannich Reaction to Synthesize Spin-Labeled Derivatives of the Natural Flavonoid Dihydroquercetin
Chemistry of Natural Compounds. 2014. V.50. N2. P.261-265. DOI: 10.1007/s10600-014-0927-7 WOS Scopus РИНЦ OpenAlex
Даты:
Опубликована в печати: 1 мая 2014 г.
Опубликована online: 13 мая 2014 г.
Идентификаторы БД:
Web of science: WOS:000336800200014
Scopus: 2-s2.0-84903160656
РИНЦ: 24061513
OpenAlex: W1993935343
Цитирование в БД:
БД Цитирований
Web of science 8
Scopus 8
РИНЦ 8
OpenAlex 7
Альметрики: