(1R,2R,4R)-N-((4-((4-(2-Carboxyethyl)phenoxy)methyl)thiophen-2-yl)methyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-aminium Chloride

(1R,2R,4R)-N-((4-((4-(2-Carboxyethyl)phenoxy)methyl)thiophen-2-yl)methyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-aminium Chloride Научная публикация

Журнал

MolBank
ISSN: 1422-8599

Вых. Данные

Год: 2023, Том: 2023, Номер: 2, Страницы: M1617 Страниц : DOI: 10.3390/m1617

Ключевые слова

FFAR1; GPR40; FFAR1 agonist; GPR40 agonist

Авторы

Kuranov Sergey O. ¹ , Marenina Mariya K. ¹ , Khvostov Mikhail V. ¹ , Luzina Olga A. ¹ , Tolstikova Tatiana G. ¹ , Salakhutdinov Nariman F. ¹

Организации

1	N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Branch of Russian Academy of Sciences

Информация о финансировании (1)

Российский Научный Фонд

21-73-00246

A novel free fatty acid receptor 1 (FFAR1) agonist has been synthesized and evaluated in vitro. The synthesis of the title compound was performed from commercially available 4-hydroxybenzaldehyde, 2-thiophenecarboxaldehyde, and (+)-camphor. The compound was shown to have an affinity to FFAR1.

Kuranov S.O. , Marenina M.K. , Khvostov M.V. , Luzina O.A. , Tolstikova T.G. , Salakhutdinov N.F.
(1R,2R,4R)-N-((4-((4-(2-Carboxyethyl)phenoxy)methyl)thiophen-2-yl)methyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-aminium Chloride
MolBank. 2023. V.2023. N2. P.M1617. DOI: 10.3390/m1617 WOS Scopus РИНЦ OpenAlex

Поступила в редакцию:	20 мар. 2023 г.
Принята к публикации:	5 апр. 2023 г.
Опубликована в печати:	7 апр. 2023 г.

Web of science:	WOS:001014507900001
Scopus:	2-s2.0-85163753620
РИНЦ:	61309526
OpenAlex:	W4363650877

БД	Цитирований
OpenAlex	1
Web of science	1