Synthesis of New Compounds Combining Adamantanamine and Monoterpene Fragments and their Antiviral Activity Against Influenza Virus A(H1N1)pdm09 Научная публикация
| Журнал |
Letters in Drug Design and Discovery
ISSN: 1570-1808 , E-ISSN: 1875-628X |
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| Вых. Данные | Год: 2013, Том: 10, Номер: 6, Страницы: 477-485 Страниц : DOI: 10.2174/1570180811310060002 | ||||
| Ключевые слова | Adamantyamine; Antiviral; (H1N1)pdm09; Influenza; Monoterpenoid; Resistance | ||||
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Реферат:
A set of new nitrogen-containing compounds with adamantane and monoterpene frameworks was synthesized. The antiviral activity of the amine products against the influenza virus A/California/07/09 (H1N1)pdm09 was studied. The introduction of a monoterpenoid fragment led to increase of the antiviral activity of adamantylamine derivatives against adamantylamine resistant virus: the selectivity index of the majority of the synthesized amines was higher than that of rimantadine and amantadine.
Библиографическая ссылка:
Teplov G.V.
, Suslov E.V.
, Zarubaev V.V.
, Shtro A.A.
, Karpinskaya L.A.
, Rogachev A.D.
, Korchagina D.V.
, Volcho K.P.
, Salakhutdinov N.F.
, Kiselev O.I.
Synthesis of New Compounds Combining Adamantanamine and Monoterpene Fragments and their Antiviral Activity Against Influenza Virus A(H1N1)pdm09
Letters in Drug Design and Discovery. 2013. V.10. N6. P.477-485. DOI: 10.2174/1570180811310060002 WOS Scopus РИНЦ OpenAlex
Synthesis of New Compounds Combining Adamantanamine and Monoterpene Fragments and their Antiviral Activity Against Influenza Virus A(H1N1)pdm09
Letters in Drug Design and Discovery. 2013. V.10. N6. P.477-485. DOI: 10.2174/1570180811310060002 WOS Scopus РИНЦ OpenAlex
Даты:
| Опубликована в печати: | 1 мая 2013 г. |
Идентификаторы БД:
| Web of science: | WOS:000318995000001 |
| Scopus: | 2-s2.0-84879756004 |
| РИНЦ: | 20438885 |
| OpenAlex: | W2321237620 |