Acylation of Azepanoglycyrrhetol | Sciact - научная деятельность

Acylation of Azepanoglycyrrhetol Научная публикация

Журнал

Chemistry of Natural Compounds
ISSN: 0009-3130 , E-ISSN: 1573-8388

Вых. Данные

Год: 2024, Том: 60, Номер: 6, Страницы: 1066-1071 Страниц : 6 DOI: 10.1007/s10600-024-04521-1

Ключевые слова

glycyrrhetinic acid synthesis azepanotriterpenoids cytotoxicity

Авторы

Terekhova A.V. ¹ , Petrova A.V. ¹ , Kazakova O.B. ¹ , Vakhitova Yu.V. ² , Polovyanenko D.N. ³ , Bagryanskaya I.Yu. ³

Организации

1	Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences
2	Institute of Biochemistry and Genetics, Ufa Federal Research Center, Russian Academy of Sciences
3	N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences

Acylation of azepano-11-deoxoglycyrrhetol synthesized N-acetyl- and N,O-bis-acetyl derivatives. The structure of azepano-11-deoxoglycyrrhetol was confirmed by an XSA. Data for its influence on cell cycle progression suggested that suppression of cell survival was due primarily to a cytostatic effect that was related to arrest of the S or G1 phase, depending on the cell line.

Terekhova A.V. , Petrova A.V. , Kazakova O.B. , Vakhitova Y.V. , Polovyanenko D.N. , Bagryanskaya I.Y.
Acylation of Azepanoglycyrrhetol
Chemistry of Natural Compounds. 2024. V.60. N6. P.1066-1071. DOI: 10.1007/s10600-024-04521-1 WOS Scopus OpenAlex

Поступила в редакцию:	10 мар. 2024 г.
Опубликована online:	8 нояб. 2024 г.

Web of science:	WOS:001351186100009
Scopus:	2-s2.0-85208783404
OpenAlex:	W4404196893

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