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Benzoquinone and naphthoquinone based redox-active labels for electrochemical detection of modified oligonucleotides on Au electrodes Научная публикация

Журнал Tetrahedron Letters
ISSN: 0040-4039
Вых. Данные Год: 2016, Том: 57, Номер: 3, Страницы: 392-395 Страниц : DOI: 10.1016/j.tetlet.2015.12.035
Ключевые слова Quinones; Redox-active labels; Electrochemical reduction; Cyclic voltammetry; Modified oligonucleotides
Авторы Shundrin Leonid A. 1,2,3 , Irtegova Irina G. 1,2 , Vasilieva Nadezhda V. 1 , Khalfina Irina A. 1,2
Организации
1 (Данные Web of science) Russian Acad Sci, Siberian Branch, NN Vorozhtsov Inst Organ Chem, Academician Lavrentev Ave 9, Novosibirsk 630090, Russia
2 (Данные Web of science) Novosibirsk State Univ, Natl Res Univ, Dept Nat Sci, Pirogova Str 2, Novosibirsk 630090, Russia
3 (Данные Web of science) Russian Acad Med Sci, Siberian Branch, Sci Inst Clin & Expt Lymphol, Timakova Str 4, Novosibirsk 630060, Russia

Реферат: The reaction of 1,4-benzoquinone and 1,4-naphthoquinone with beta-thiopropionic acid yielded 3-[(3,6-dioxocyclohexa-1,4-diene-1-yl)thio]propionic and 3-[(1,4-dioxo-1,4-dihydronaphthalene-2-yl)thio]propionic acids, respectively. These compounds were used to modify oligonucleotides to allow their electrochemical detection on the surface of Au electrodes using cyclic voltammetry. Electrochemical reduction of the corresponding amides, modeling the bonding of the redox-active labels with molecules that are not electrochemically active, was also studied. (C) 2015 Elsevier Ltd. All rights reserved.
Библиографическая ссылка: Shundrin L.A. , Irtegova I.G. , Vasilieva N.V. , Khalfina I.A.
Benzoquinone and naphthoquinone based redox-active labels for electrochemical detection of modified oligonucleotides on Au electrodes
Tetrahedron Letters. 2016. V.57. N3. P.392-395. DOI: 10.1016/j.tetlet.2015.12.035 WOS Scopus РИНЦ OpenAlex
Даты:
Опубликована в печати: 1 янв. 2016 г.
Идентификаторы БД:
Web of science: WOS:000369556900039
Scopus: 2-s2.0-84953362834
РИНЦ: 26929366
OpenAlex: W2217904519
Цитирование в БД:
БД Цитирований
Web of science 9
Scopus 9
РИНЦ 9
OpenAlex 10
Альметрики: