3-Carboxy-2,2,5,5-tetra(H-2(3))methyl-[4-H-2 (H-1)]-3-pyrroline-(1-N-15)-1-oxyl as a spin probe for in vivo L-band electron paramagnetic resonance imaging

3-Carboxy-2,2,5,5-tetra(H-2(3))methyl-[4-H-2 (H-1)]-3-pyrroline-(1-N-15)-1-oxyl as a spin probe for in vivo L-band electron paramagnetic resonance imaging Научная публикация

Журнал

Mendeleev Communications
ISSN: 0959-9436

Вых. Данные

Год: 2014, Том: 24, Номер: 5, Страницы: 298-300 Страниц : DOI: 10.1016/j.mencom.2014.09.017

Авторы

Shundrin Leonid A. ^1,2,3 , Kirilyuk Igor A. ^1,2 , Grigor'ev Igor A. ^1,4

Организации

1	(Данные Web of science) Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, Novosibirsk 630090, Russia
2	(Данные Web of science) Novosibirsk State Univ, Dept Nat Sci, Novosibirsk 630090, Russia
3	(Данные Web of science) Sci Inst Clin & Expt Lymphol, Novosibirsk 630060, Russia
4	(Данные Web of science) EN Meshalkin State Res Inst Circulat Pathol, Novosibirsk 630055, Russia

The suitability of 3-Carboxy-2,2,5,5-tetra(H-2(3))methyl-[4-H-2 (H-1)]-3-pyrroline-(1-N-15)-1-oxyl and its non-deuterated N-14-containing nitroxide analogue for L-band EPR in vivo imaging has been demonstrated. Both nitroxides exhibit low rates of reduction with ascorbate and slow decay in mice blood and plasma and, according to the EPR data, accumulate in the liver of a living mice within 10-70 min after the injection via tail vein, and then collect in the bladder.

Shundrin L.A. , Kirilyuk I.A. , Grigor'ev I.A.
3-Carboxy-2,2,5,5-tetra(H-2(3))methyl-[4-H-2 (H-1)]-3-pyrroline-(1-N-15)-1-oxyl as a spin probe for in vivo L-band electron paramagnetic resonance imaging
Mendeleev Communications. 2014. V.24. N5. P.298-300. DOI: 10.1016/j.mencom.2014.09.017 WOS Scopus РИНЦ

Опубликована в печати:

1 сент. 2014 г.

Web of science	WOS:000344137100017
Scopus	2-s2.0-84908570716
РИНЦ	23997904
OpenAlex	W2029676086