SYNTHESIS OF HYBRID MOLECULES CONTAINING FRAGMENTS OF SESQUITERPENE LACTONES AND PLANT ALKALOIDS

SYNTHESIS OF HYBRID MOLECULES CONTAINING FRAGMENTS OF SESQUITERPENE LACTONES AND PLANT ALKALOIDS Научная публикация

Журнал

Chemistry of Natural Compounds
ISSN: 0009-3130 , E-ISSN: 1573-8388

Вых. Данные

Год: 2011, Том: 46, Номер: 6, Страницы: 880-885 Страниц : DOI: 10.1007/s10600-011-9774-y

Ключевые слова

isoalantolactone; 5'-iodolappaconitine; 6-bromodeoxyvasicinone; Pd acetate; cross-coupling reaction

Авторы

Belovodskii A. V. ¹ , Shul'ts E. E. ¹ , Shakirov M. M. ¹ , Romanov V. E. ¹ , Elmuradov B. Zh. ² , Shakhidoyatov Kh. M. ² , Tolstikov G. A. ¹

Организации

1	(Данные Web of science) Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia
2	(Данные Web of science) Acad Sci Uzbek, S Yu Yunusov Inst Chem Plant Subst, Tashkent, Uzbekistan

The Pd-catalyzed arylation of isoalantolactone by deoxyvasicinone and lappaconitine halides occurred with formation mainly of cross-coupling products with the (E)-configuration of the double bond. Another three compounds were isolated from the reaction of isoalantolactone with 6-bromodeoxyvasicinone. These were the lactone diarylation product, a compound with the (Z)-configuration of the double bond, and a product with a shift of the C(11,13) double bond and configuration inversion at C(8). The new compounds are interesting as potential biologically active agents.

Belovodskii A.V. , Shul'ts E.E. , Shakirov M.M. , Romanov V.E. , Elmuradov B.Z. , Shakhidoyatov K.M. , Tolstikov G.A.
SYNTHESIS OF HYBRID MOLECULES CONTAINING FRAGMENTS OF SESQUITERPENE LACTONES AND PLANT ALKALOIDS
Chemistry of Natural Compounds. 2011. V.46. N6. P.880-885. DOI: 10.1007/s10600-011-9774-y WOS Scopus РИНЦ

Опубликована в печати:	1 янв. 2011 г.
Опубликована online:	8 февр. 2011 г.

Web of science	WOS:000288438500011
Scopus	2-s2.0-79952696502
РИНЦ	24939318
OpenAlex	W2009522262