A facile approach to hybrid compounds containing a tricyclic diterpenoid and fluorine-substituted heterocycles

A facile approach to hybrid compounds containing a tricyclic diterpenoid and fluorine-substituted heterocycles Научная публикация

Журнал

Journal of Fluorine Chemistry
ISSN: 0022-1139

Вых. Данные

Год: 2020, Том: 236, Номер статьи : 109554, Страниц : DOI: 10.1016/j.jfluchem.2020.109554

Ключевые слова

Fluorinated heterocycles; 2H-chromenes; Benzofurans; Isopimaric acid; Terpenoid allene; Cross-coupling-cyclization

Авторы

Gromova M.A. ¹ , Kharitonov Yu, V ¹ , Politanskaya L., V ¹ , Tretyakov E., V ^1,2 , Shults E.E. ¹

Организации

1	(Данные Web of science) Novosibirsk Inst Organ Chem SB RAS, Lavrengev Ave 9, Novosibirsk 630090, Russia
2	(Данные Web of science) Novosibirsk State Univ, Pirogova St 2, Novosibirsk 630090, Russia

2,3-Butadienes have become valuable building blocks in the synthesis of various heterocyclic compounds. The Pd-catalyzed cross-coupling and cyclization reaction of N-(2,3-butadienyl)carboxamide of isopimaric acid with fluorine-substituted 2-iodophenols proceeds with the formation of optically active fluorinated benzofuran and benzopyrane derivatives of isopimaric acid. This transformation opens a potential route to the synthesis of hybrid compounds containing a tricyclic diterpenoid moiety and several fluorinated benzoannelated heterocycles.

Gromova M.A. , Kharitonov Y.V. , Politanskaya L.,.V. , Tretyakov E.,.V. , Shults E.E.
A facile approach to hybrid compounds containing a tricyclic diterpenoid and fluorine-substituted heterocycles
Journal of Fluorine Chemistry. 2020. V.236. 109554 . DOI: 10.1016/j.jfluchem.2020.109554 WOS Scopus РИНЦ

Опубликована в печати:

1 авг. 2020 г.

Web of science	WOS:000551145100004
Scopus	2-s2.0-85085295681
РИНЦ	43293186
OpenAlex	W3025522951