Synthesis of 1,5,6,7-Tetrahydro-4H- benzimidazol-4-one Derivatives from 2,6-Bis(hydroxyimino)cyclohexan-1-one

Synthesis of 1,5,6,7-Tetrahydro-4H- benzimidazol-4-one Derivatives from 2,6-Bis(hydroxyimino)cyclohexan-1-one Научная публикация

Журнал

Russian Journal of Organic Chemistry
ISSN: 1070-4280 , E-ISSN: 1608-3393

Вых. Данные

Год: 2017, Том: 53, Номер: 1, Страницы: 66-73 Страниц : 8 DOI: 10.1134/S1070428017010122

Авторы

Samsonov V.A. ¹

Организации

1	(Данные Web of science) Russian Acad Sci, Siberian Branch, Vorozhtsov Novosibirsk Inst Organ Chem, Pr Akad Lavrenteva 9, Novosibirsk 630090, Russia

The reaction of 2,6-bis(hydroxyimino)cyclohexan-1-one with aldehydes and ammonia afforded 2-substituted 4-hydroxyimino-4,5,6,7-tetrahydro-1H-benzimidazol-1-ols which were hydrolyzed to 1-hydroxy2- R-1,5,6,7-tetrahydro-4H-benzimidazol-4-ones. The N-hydroxy group in the latter can readily by removed by the action of chloroacetone in the presence of a base (potassium carbonate or triethylamine); as a result, 2-substituted 1,5,6,7-tetrahydro-4H-benzimidazol-4-ones were obtained.

Samsonov V.A.
Synthesis of 1,5,6,7-Tetrahydro-4H- benzimidazol-4-one Derivatives from 2,6-Bis(hydroxyimino)cyclohexan-1-one
Russian Journal of Organic Chemistry. 2017. V.53. N1. P.66-73. DOI: 10.1134/S1070428017010122 WOS Scopus РИНЦ

Самсонов В.А.
Синтез производных 1,5,6,7-тетрагидро- 4н-бензимидазол-4-она на основе 2,6- бис(гидроксиимино)циклогексан-1 -она
Журнал органической химии (RUSS J ORG CHEM+). 2017. Т.53. №1. С.71-77. РИНЦ

Опубликована в печати:	1 янв. 2017 г.
Опубликована online:	8 мар. 2017 г.

Web of science	WOS:000396525200012
Scopus	2-s2.0-85014865828
РИНЦ	29488922
OpenAlex	W2593720562