Study of skin anti-ageing and anti-inflammatory effects of dihydroquercetin, natural triterpenoinds, and their synthetic derivatives Научная публикация
| Журнал |
Russian Journal of Bioorganic Chemistry
ISSN: 1068-1620 |
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| Вых. Данные | Год: 2012, Том: 38, Номер: 3, Страницы: 328-334 Страниц : DOI: 10.1134/S1068162012030028 | ||||||||
| Ключевые слова | collagenase-1; triterpenoids; dihydroquercetin; photoageing; interleukin-8 | ||||||||
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Реферат:
Accessible triterpenoids of ursane and lupane series, the flavonoid dihydroquercetin and their synthetic derivatives with polar substituents were tested in vitro for inhibition of collagenase 1 (MMP-1) in UVB irradiation assay. Ursolic acid and uvaol disuccinate were the most active inhibitors in the ursane series. In the lupane series, the best inhibition was manifested by carboxymethyl ester of betulonic acid and betulin succinates. Down- regulation of MMP-1 by dihydroquercetin and its synthetic derivatives surpassed the activity of a standard (retinoic acid).
Библиографическая ссылка:
Lee C.W.
, Park N.H.
, Kim J.W.
, Um B.H.
, Shpatov A.V.
, Shults E.E.
, Sorokina I.V.
, Popov S.A.
Study of skin anti-ageing and anti-inflammatory effects of dihydroquercetin, natural triterpenoinds, and their synthetic derivatives
Russian Journal of Bioorganic Chemistry. 2012. V.38. N3. P.328-334. DOI: 10.1134/S1068162012030028 WOS Scopus РИНЦ OpenAlex
Study of skin anti-ageing and anti-inflammatory effects of dihydroquercetin, natural triterpenoinds, and their synthetic derivatives
Russian Journal of Bioorganic Chemistry. 2012. V.38. N3. P.328-334. DOI: 10.1134/S1068162012030028 WOS Scopus РИНЦ OpenAlex
Даты:
| Опубликована в печати: | 1 мая 2012 г. |
| Опубликована online: | 23 мая 2012 г. |
Идентификаторы БД:
| Web of science: | WOS:000304408900013 |
| Scopus: | 2-s2.0-84865457787 |
| РИНЦ: | 20471406 |
| OpenAlex: | W2028426733 |