Synthesis of 5,5-Disubstituted N-Methyl-1,3-oxazinanes Containing Monoterpene Fragments

Synthesis of 5,5-Disubstituted N-Methyl-1,3-oxazinanes Containing Monoterpene Fragments Научная публикация

Журнал

Doklady Chemistry
ISSN: 0012-5008

Вых. Данные

Год: 2023, Том: 512 part 2, Страницы: 281-287 Страниц : 7 DOI: 10.1134/S001250082360058X

Ключевые слова

oxazine, tetrahydro-1,3-oxazine, oxazinane, aminopropanol, propanolamine, pinene, Knoevenagel condensation, alkylation of cyanoacetic ester, ethyl cyanoacetate

Авторы

Nechepurenko I.V. ¹ , Volcho K.P. ¹ , Salakhutdinov N.F. ¹

Организации

1	Vorozhtsov Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090 Russia

A new method has been developed for the synthesis of 5,5-disubstituted N-methyl-1,3-oxazinanes as a mixture of diastereomers at the 5-position containing monoterpene and branched alkyl substituents in the 5-position. 1,3-Oxazinanes were obtained for the first time by reacting 2,2-substituted 3-aminopropan-1-ols with formaldehyde and sodium borohydride in one stage.

Nechepurenko I.V. , Volcho K.P. , Salakhutdinov N.F.
Synthesis of 5,5-Disubstituted N-Methyl-1,3-oxazinanes Containing Monoterpene Fragments
Doklady Chemistry. 2023. V.512 part 2. P.281-287. DOI: 10.1134/S001250082360058X WOS РИНЦ

Нечепуренко И.В. , Волчо К.П. , Салахутдинов Н.Ф.
СИНТЕЗ 5,5-ДИЗАМЕЩЕННЫХ N-МЕТИЛ-1,3-ОКСАЗИНАНОВ, СОДЕРЖАЩИХ МОНОТЕРПЕНОВЫЕ ФРАГМЕНТЫ
Доклады Российской академии наук. Химия, науки о материалах.. 2023. Т.512. С.75-82. DOI: 10.31857/S2686953522600283 РИНЦ

Поступила в редакцию:	9 июн. 2022 г.
Принята к публикации:	21 нояб. 2022 г.

Web of science	WOS:001130184300001
РИНЦ	65019761
OpenAlex	W4390191029